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KMID : 0358420110540070381
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 7 p.381 ~ p.385
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A case of vaginal delivery in β-thalassemia minor pregnant woman
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Shim Hyun-Jin
Jo Eun-Kyu
Jeon Hye-Ji
Lee Mi-Ra
Kim Yun-Sook
Bae Dong-Han
Kim Hui-Jun
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Abstract
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The thalassemias are a group of autosomal recessive genetic disorders of hemoglobin synthesis. The thalassemias are classified into two main varieties, α- and β-, depending on which of the adult globin chain is produced in reduced amounts. The β-thalassemia is the homozygous and heterozygous state, and common in the Mediterranean region. Homozygous β-thalassemia is usually associated with severe anemia. β-Thalassemia minor, the heterozygous state, is characterized by hypochromia, microcytosis and an elevated of HgA2. No treatment is required for thalassemia minor, but it is important to exclude iron deficiency anemia and postpartum genetic counseling. Recently, β-thalassemia minor keeps rising steadily in Korea due to the increase in international marriges. Recently we have experienced a vaginal delivery in a β-thalassemia minor Vietnam woman associated with mild anemia. We describe this case with a brief review of the literature.
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KEYWORD
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β-Thalassemia, Anemia, Delivery
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